The key ingredient: Olivetol

Undoo’s training guide points to olivetol as the core ingredient and frames it with the classic “lock and key” model: CB1/CB2 receptors as locks, cannabinoids as keys.

The patent describes olivetol (5-pentylresorcinol) as a naturally occurring compound found in certain lichens and other sources, with structural similarity to cannabinoid chemistry, and notes its role as a precursor used in THC synthesis in lab contexts. 

Why the softgel is oil-based

Olivetol is described in the patent as fat soluble, meaning it should be combined with an edible oil for best absorption in the GI tract. One example formulation listed is 30 mg olivetol + 750 mg olive oil + 10 mg vitamin E per softgel.

That oil detail matters for a mundane reason: compounds that dissolve in fats tend to behave poorly in water-only delivery.

The proposed mechanism: competitive inhibition at CB1/CB2

The patent’s core claim is that olivetol acts as a competitive inhibitor at cannabinoid receptors CB1 and CB2. The description goes further:

• It is believed olivetol binds more tightly and/or more aggressively than THC.

• It is described as having a lower dissociation constant, staying in the receptor’s active site longer.

• It is described as not activating the receptor in the same way THC does, and therefore not producing the downstream change in GABA release that the patent ties to THC’s psychotropic effects. 

In plain terms: the patent’s model is “occupy the parking spot, don’t start the engine.” THC has fewer available receptors to bind to, so the subjective “high” can drop.

What evidence the patent actually presents

The patent includes “real-life, non-clinical” volunteer examples where subjects reported a noticeable reduction in cannabis effects within roughly 4–10 minutes after taking a softgel dose, often paired with self-reported increases in mental clarity. 

That’s useful context, with a big asterisk: these are informal reports, not blinded clinical trials. A patent can describe a mechanism and claim methods; it is not a substitute for published human research.

How Undoo Reset turns that into a “tolerance reset” protocol

Undoo’s budtender training guide recommends:

• 2 softgels

• 12–16 oz of water

• Before bed

• For 5 consecutive nights 

The guide stresses following directions closely, including a ceiling of no more than 6 softgels in a 24-hour period, and warns customers to be careful after the reset because effects may feel stronger than expected. 

The implied logic is straightforward: if competitive inhibition reduces THC receptor binding in the moment, repeating that pattern nightly may change your baseline experience when you return to your usual dose.

What a careful reader should take away

• The materials describe a receptor-competition theory for why effects might change. 

• The supporting “data” shown in the patent is informal self-reporting. 

• The reset protocol and guardrails (hydration, timing, max daily amount, “watch your dose after”) come from Undoo’s training guide.